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Shikonin inhibits proliferation of melanoma cells by MAPK pathway-mediated induction of apoptosis

Shikonin, a natural product isolated from the roots of Lithospermum erythrorhizon, exhibits pharmacological effects against inflammation, ulcers, infections, and tumors. In the present study, we aimed to investigate the antitumor effects of shikonin on the human melanoma cell line, A375SM, and in an...

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Detalles Bibliográficos
Autores principales: Lee, Jae Han, Han, So Hee, Kim, You Min, Kim, Sung Hyun, Yoo, Eun Seon, Woo, Joong Seok, Jung, Gi Hwan, Jung, Soo Hyun, Kim, Bum Seok, Jung, Ji Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823184/
https://www.ncbi.nlm.nih.gov/pubmed/33403388
http://dx.doi.org/10.1042/BSR20203834