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Reflection on modern methods: trial emulation in the presence of immortal-time bias. Assessing the benefit of major surgery for elderly lung cancer patients using observational data

Acquiring real-world evidence is crucial to support health policy, but observational studies are prone to serious biases. An approach was recently proposed to overcome confounding and immortal-time biases within the emulated trial framework. This tutorial provides a step-by-step description of the d...

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Detalles Bibliográficos
Autores principales: Maringe, Camille, Benitez Majano, Sara, Exarchakou, Aimilia, Smith, Matthew, Rachet, Bernard, Belot, Aurélien, Leyrat, Clémence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823243/
https://www.ncbi.nlm.nih.gov/pubmed/32386426
http://dx.doi.org/10.1093/ije/dyaa057