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Complete Cocrystal Formation during Resonant Acoustic Wet Granulation: Effect of Granulation Liquids

The manufacturing of solid pharmaceutical dosage forms composed of cocrystals requires numerous processes during which there is risk of dissociation into parent molecules. Resonant acoustic wet granulation (RAG) was devised in an effort to complete theophylline–citric acid (THPCIT) cocrystal formati...

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Detalles Bibliográficos
Autores principales: Tanaka, Ryoma, Osotprasit, Supisara, Peerapattana, Jomjai, Ashizawa, Kazuhide, Hattori, Yusuke, Otsuka, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823328/
https://www.ncbi.nlm.nih.gov/pubmed/33406659
http://dx.doi.org/10.3390/pharmaceutics13010056