The Ubiquitin Ligase SIAH2 Negatively Regulates Glucocorticoid Receptor Activity and Abundance

Glucocorticoids are clinically essential drugs used routinely to control inflammation. However, a host of metabolic side effects manifests upon usage beyond a few days. In the present study, we tested the hypothesis that seven-in-absentia mammalian homolog-2 (SIAH2), a ubiquitin ligase that regulate...

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Detalles Bibliográficos
Autores principales: Burke, Susan J., Taylor, Jessica L., Batdorf, Heidi M., Noland, Robert C., Burk, David H., Yu, Yongmei, Floyd, Z. Elizabeth, Collier, J. Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823448/
https://www.ncbi.nlm.nih.gov/pubmed/33396678
http://dx.doi.org/10.3390/biomedicines9010022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823448/
https://www.ncbi.nlm.nih.gov/pubmed/33396678
http://dx.doi.org/10.3390/biomedicines9010022

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