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Mechanistic Insight into the Regulation of Lipoxygenase-Driven Lipid Peroxidation Events in Human Spermatozoa and Their Impact on Male Fertility

A prevalent cause of sperm dysfunction in male infertility patients is the overproduction of reactive oxygen species, an attendant increase in lipid peroxidation and the production of cytotoxic reactive carbonyl species such as 4-hydroxynonenal. Our previous studies have implicated arachidonate 15-l...

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Detalles Bibliográficos
Autores principales: Walters, Jessica L. H., Anderson, Amanda L., Martins da Silva, Sarah J., Aitken, R. John, De Iuliis, Geoffry N., Sutherland, Jessie M., Nixon, Brett, Bromfield, Elizabeth G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823465/
https://www.ncbi.nlm.nih.gov/pubmed/33396527
http://dx.doi.org/10.3390/antiox10010043