Discovery of Potent Dual EGFR/HER2 Inhibitors Based on Thiophene Scaffold Targeting H1299 Lung Cancer Cell Line

Dual targeting of epidermal growth factor receptor (EGFR) and human EGFR-related receptor 2 (HER2) is a proven approach for the treatment of lung cancer. With the aim of discovering effective dual EGFR/HER2 inhibitors targeting non-small cell lung cancer cell line H1299, three series of thieno[2,3-d...

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Detalles Bibliográficos
Autores principales: Elrayess, Ranza, Abdel Aziz, Yasmine M., Elgawish, Mohamed Saleh, Elewa, Marwa, Yassen, Asmaa S. A., Elhady, Sameh S., Elshihawy, Hosam A., Said, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823583/
https://www.ncbi.nlm.nih.gov/pubmed/33374155
http://dx.doi.org/10.3390/ph14010009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823583/
https://www.ncbi.nlm.nih.gov/pubmed/33374155
http://dx.doi.org/10.3390/ph14010009

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