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Synthesis and In Vitro Assessment of pH-Sensitive Human Serum Albumin Conjugates of Pirarubicin

In a previous study, we reported on the development of a synthetic polymer conjugate of pirarubicin (THP) that was formed via an acid-labile hydrazone bond between the polymer and the THP. However, the synthetic polymer itself was non-biodegradable, which could lead to unexpected adverse effects. Hu...

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Detalles Bibliográficos
Autores principales: Tsukigawa, Kenji, Imoto, Shuhei, Yamasaki, Keishi, Nishi, Koji, Tsutsumi, Toshihiko, Yokoyama, Shoko, Ishima, Yu, Otagiri, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823624/
https://www.ncbi.nlm.nih.gov/pubmed/33396604
http://dx.doi.org/10.3390/ph14010022