Cargando…

Synthesis and In Vitro Assessment of pH-Sensitive Human Serum Albumin Conjugates of Pirarubicin

In a previous study, we reported on the development of a synthetic polymer conjugate of pirarubicin (THP) that was formed via an acid-labile hydrazone bond between the polymer and the THP. However, the synthetic polymer itself was non-biodegradable, which could lead to unexpected adverse effects. Hu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsukigawa, Kenji, Imoto, Shuhei, Yamasaki, Keishi, Nishi, Koji, Tsutsumi, Toshihiko, Yokoyama, Shoko, Ishima, Yu, Otagiri, Masaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823624/ https://www.ncbi.nlm.nih.gov/pubmed/33396604 http://dx.doi.org/10.3390/ph14010022

Ejemplares similares

Synthesis and therapeutic effect of styrene–maleic acid copolymer-conjugated pirarubicin
por: Tsukigawa, Kenji, et al.
Publicado: (2015)

Chlorine Atoms of an Aripiprazole Molecule Control the Geometry and Motion of Aripiprazole and Deschloro-aripiprazole in Subdomain IIIA of Human Serum Albumin
por: Kawai, Akito, et al.
Publicado: (2022)

Metal-catalyzed oxidation of human serum albumin does not alter the interactive binding to the two principal drug binding sites
por: Yamasaki, Keishi, et al.
Publicado: (2018)

Preparation, Characterization, and in Vitro/in Vivo Evaluation of Paclitaxel-Bound Albumin-Encapsulated Liposomes for the Treatment of Pancreatic Cancer
por: Okamoto, Yuko, et al.
Publicado: (2019)

Effects of Myristate on the Induced Circular Dichroism Spectra of Aripiprazole Bound to Human Serum Albumin: A Structural–Chemical Investigation
por: Hirata, Kenshiro, et al.
Publicado: (2022)

Analysis of the Binding of Aripiprazole to Human Serum Albumin: The Importance of a Chloro-Group in the Chemical Structure
por: Sakurama, Keiki, et al.
Publicado: (2018)

Crystal structure analysis of human serum albumin complexed with sodium 4-phenylbutyrate
por: Kawai, Akito, et al.
Publicado: (2018)

Study of the Structural Chemistry of the Inclusion Complexation of 4-Phenylbutyrate and Related Compounds with Cyclodextrins in Solution: Differences in Inclusion Mode with Cavity Size Dependency
por: Commey, Kindness L., et al.
Publicado: (2023)

Long chain fatty acids alter the interactive binding of ligands to the two principal drug binding sites of human serum albumin
por: Yamasaki, Keishi, et al.
Publicado: (2017)

Differential Effects of Methoxy Group on the Interaction of Curcuminoids with Two Major Ligand Binding Sites of Human Serum Albumin
por: Sato, Hiroki, et al.
Publicado: (2014)

S-Nitrosylated Human Serum Albumin-mediated Cytoprotective Activity Is Enhanced by Fatty Acid Binding
por: Ishima, Yu, et al.
Publicado: (2008)

Pharmacokinetic properties of a novel inosine analog, 4′-cyano-2′-deoxyinosine, after oral administration in rats
por: Hashimoto, Mai, et al.
Publicado: (2018)

Poly-S-Nitrosated Albumin as a Safe and Effective Multifunctional Antitumor Agent: Characterization, Biochemistry and Possible Future Therapeutic Applications
por: Ishima, Yu, et al.
Publicado: (2013)

The Therapeutic Effect of Human Serum Albumin Dimer-Doxorubicin Complex against Human Pancreatic Tumors
por: Kinoshita, Ryo, et al.
Publicado: (2021)

Therapeutic Impact of Human Serum Albumin–Thioredoxin Fusion Protein on Influenza Virus-Induced Lung Injury Mice
por: Tanaka, Ryota, et al.
Publicado: (2014)

A novel S-sulfhydrated human serum albumin preparation suppresses melanin synthesis
por: Ikeda, Mayumi, et al.
Publicado: (2017)

N-acetyl-L-methionine is a superior protectant of human serum albumin against post-translational oxidation as compared to N-acetyl-L-tryptophan
por: Kouno, Yousuke, et al.
Publicado: (2016)

Membrane Transport and Antitumor Activity of Pirarubicin, and Comparison with Those of Doxorubicin
por: Sugiyama, Tomomi, et al.
Publicado: (1999)

Potential Use of Biological Proteins for Liver Failure Therapy
por: Taguchi, Kazuaki, et al.
Publicado: (2015)

Comparison of the Pharmacokinetic Properties of Hemoglobin-Based Oxygen Carriers
por: Taguchi, Kazuaki, et al.
Publicado: (2017)

Poly-S-nitrosated human albumin enhances the antitumor and antimetastasis effect of bevacizumab, partly by inhibiting autophagy through the generation of nitric oxide
por: Ishima, Yu, et al.
Publicado: (2015)

Possibility of Contribution of Nucleoside Transport Systems to Pirarubicin Uptake by HL60 Cells but Not Mononuclear Cells
por: Nagasawa, Kazuki, et al.
Publicado: (1998)

Effect of Tumor Targeted-Anthracycline Nanomedicine, HPMA Copolymer-Conjugated Pirarubicin (P-THP) against Gynecological Malignancies
por: Yanazume, Shintaro, et al.
Publicado: (2022)

Long-Term Stored Hemoglobin-Vesicles, a Cellular Type of Hemoglobin-Based Oxygen Carrier, Has Resuscitative Effects Comparable to That for Fresh Red Blood Cells in a Rat Model with Massive Hemorrhage without Post-Transfusion Lung Injury
por: Tokuno, Masahiro, et al.
Publicado: (2016)

Cys34-Cysteinylated Human Serum Albumin Is a Sensitive Plasma Marker in Oxidative Stress-Related Chronic Diseases
por: Nagumo, Kohei, et al.
Publicado: (2014)

Pharmacology and antitumour effects of intraportal pirarubicin on experimental liver metastases.
por: Ramirez, L. H., et al.
Publicado: (1993)

The Binding of Aripiprazole to Plasma Proteins in Chronic Renal Failure Patients
por: Hirata, Kenshiro, et al.
Publicado: (2021)

Evaluation of cytochrome P450-based drug metabolism in hemorrhagic shock rats that were transfused with native and an artificial red blood cell preparation, Hemoglobin-vesicles
por: Tokuno, Masahiro, et al.
Publicado: (2020)

In vitro and in vivo studies of pirarubicin-loaded SWNT for the treatment of bladder cancer
por: Chen, Gang, et al.
Publicado: (2012)

Application of pirarubicin photosensitizer fluorescence cystoscopy in early detection of bladder cancer
por: Jiang, Bo, et al.
Publicado: (2017)

Development of a Selective Tumor-Targeted Drug Delivery System: Hydroxypropyl-Acrylamide Polymer-Conjugated Pirarubicin (P-THP) for Pediatric Solid Tumors
por: Makimoto, Atsushi, et al.
Publicado: (2021)

Carbon monoxide-bound hemoglobin vesicles ameliorate multiorgan injuries induced by severe acute pancreatitis in mice by their anti-inflammatory and antioxidant properties
por: Nagao, Saori, et al.
Publicado: (2016)

Characteristics of the Inhibitory Effect of Mitoxantrone and Pirarubicin on Lung Metastases of Colon Carcinoma 26
por: Iigo, Masaaki, et al.
Publicado: (1995)

Serum Albumin–Peptide Conjugates for Simultaneous Heparin Binding and Detection
por: Liu, Qing, et al.
Publicado: (2019)

Physicochemical Properties of Bovine Serum Albumin-Glucose and Bovine Serum Albumin-Mannose Conjugates Prepared by Pulsed Electric Fields Treatment
por: Jian, Wenjie, et al.
Publicado: (2018)

Transarterial chemoembolization with pirarubicin-eluting microspheres in patients with unresectable hepatocellular carcinoma: Preliminary results
por: Bai, Mingjun, et al.
Publicado: (2019)

Reducing oxidative stress may be important for treating pirarubicin-induced cardiotoxicity with schisandrin B
por: Tang, Heng, et al.
Publicado: (2022)

Dopamine-Conjugated Bovine Serum Albumin Nanoparticles Containing pH-Responsive Catechol-V(III) Coordination for In Vitro and In Vivo Drug Delivery
por: Argitekin, Eda, et al.
Publicado: (2023)

Binding of estrogen receptor with estrogen conjugated to bovine serum albumin (BSA)
por: Taguchi, Yasuto, et al.
Publicado: (2004)

Photosensitizer-Conjugated Human Serum Albumin Nanoparticles for Effective Photodynamic Therapy
por: Jeong, Hayoung, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_5v0n3ebpqskciqpdvsd60f5j6n