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Evaluation of a Microhaplotype-Based Noninvasive Prenatal Test in Twin Gestations: Determination of Paternity, Zygosity, and Fetal Fraction

As a novel type of genetic marker, the microhaplotype has shown promising potential in forensic research. In the present study, we analyzed maternal plasma cell-free DNA (cfDNA) samples from twin pregnancies to validate microhaplotype-based noninvasive prenatal testing (NIPT) for paternity, zygosity...

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Detalles Bibliográficos
Autores principales: Bai, Zhaochen, Zhao, Hu, Lin, Shaobin, Huang, Linhuan, He, Zhiming, Wang, Huan, Ou, Xueling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823673/
https://www.ncbi.nlm.nih.gov/pubmed/33375453
http://dx.doi.org/10.3390/genes12010026