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Evaluation of a Microhaplotype-Based Noninvasive Prenatal Test in Twin Gestations: Determination of Paternity, Zygosity, and Fetal Fraction
As a novel type of genetic marker, the microhaplotype has shown promising potential in forensic research. In the present study, we analyzed maternal plasma cell-free DNA (cfDNA) samples from twin pregnancies to validate microhaplotype-based noninvasive prenatal testing (NIPT) for paternity, zygosity...
Autores principales: | Bai, Zhaochen, Zhao, Hu, Lin, Shaobin, Huang, Linhuan, He, Zhiming, Wang, Huan, Ou, Xueling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823673/ https://www.ncbi.nlm.nih.gov/pubmed/33375453 http://dx.doi.org/10.3390/genes12010026 |
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