Activation of Serum/Glucocorticoid Regulated Kinase 1/Nuclear Factor-κB Pathway Are Correlated with Low Sensitivity to Bortezomib and Ixazomib in Resistant Multiple Myeloma Cells

Multiple myeloma (MM) is an incurable malignancy often associated with primary and acquired resistance to therapeutic agents, such as proteasome inhibitors. However, the mechanisms underlying the proteasome inhibitor resistance are poorly understood. Here, we elucidate the mechanism of primary resis...

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Detalles Bibliográficos
Autores principales: Tsubaki, Masanobu, Takeda, Tomoya, Matsuda, Takuya, Seki, Shiori, Tomonari, Yoshika, Koizumi, Shoutaro, Nagatakiya, Miki, Katsuyama, Mai, Yamamoto, Yuuta, Tsurushima, Katsumasa, Ishizaka, Toshihiko, Nishida, Shozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823718/
https://www.ncbi.nlm.nih.gov/pubmed/33406639
http://dx.doi.org/10.3390/biomedicines9010033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823718/
https://www.ncbi.nlm.nih.gov/pubmed/33406639
http://dx.doi.org/10.3390/biomedicines9010033

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