NLRP1 Functions Downstream of the MAPK/ERK Signaling via ATF4 and Contributes to Acquired Targeted Therapy Resistance in Human Metastatic Melanoma

The BRAF V600E mutation leads to constitutive activation of the mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) pathway and its downstream effector responses. Uncovering the hidden downstream effectors can aid in understanding melanoma biology and improve targeted...

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Detalles Bibliográficos
Autores principales: Zhai, Zili, Vaddi, Prasanna K., Samson, Jenny Mae, Takegami, Tomoya, Fujita, Mayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823742/
https://www.ncbi.nlm.nih.gov/pubmed/33396632
http://dx.doi.org/10.3390/ph14010023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823742/
https://www.ncbi.nlm.nih.gov/pubmed/33396632
http://dx.doi.org/10.3390/ph14010023

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