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Structural Variability, Expression Profile, and Pharmacogenetic Properties of TMPRSS2 Gene as a Potential Target for COVID-19 Therapy

The human serine protease serine 2 TMPRSS2 is involved in the priming of proteins of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and represents a possible target for COVID-19 therapy. The TMPRSS2 gene may be co-expressed with SARS-CoV-2 cell receptor genes angiotensin-converting...

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Detalles Bibliográficos
Autores principales: Zarubin, Aleksei, Stepanov, Vadim, Markov, Anton, Kolesnikov, Nikita, Marusin, Andrey, Khitrinskaya, Irina, Swarovskaya, Maria, Litvinov, Sergey, Ekomasova, Natalia, Dzhaubermezov, Murat, Maksimova, Nadezhda, Sukhomyasova, Aitalina, Shtygasheva, Olga, Khusnutdinova, Elza, Radzhabov, Magomed, Kharkov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823984/
https://www.ncbi.nlm.nih.gov/pubmed/33375616
http://dx.doi.org/10.3390/genes12010019