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Evogliptin Suppresses Calcific Aortic Valve Disease by Attenuating Inflammation, Fibrosis, and Calcification

Calcific aortic valve disease (CAVD) accompanies inflammatory cell infiltration, fibrosis, and ultimately calcification of the valve leaflets. We previously demonstrated that dipeptidyl peptidase-4 (DPP-4) is responsible for the progression of aortic valvular calcification in CAVD animal models. As...

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Detalles Bibliográficos
Autores principales: Choi, Bongkun, Kim, Eun-Young, Kim, Ji-Eun, Oh, Soyoon, Park, Si-On, Kim, Sang-Min, Choi, Hyuksu, Song, Jae-Kwan, Chang, Eun-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824080/
https://www.ncbi.nlm.nih.gov/pubmed/33401457
http://dx.doi.org/10.3390/cells10010057