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Senescence-Associated Secretory Phenotype Suppression Mediated by Small-Sized Mesenchymal Stem Cells Delays Cellular Senescence through TLR2 and TLR5 Signaling

In order to provide a sufficient number of cells for clinical use, mesenchymal stem cells (MSCs) must be cultured for long-term expansion, which inevitably triggers cellular senescence. Although the small size of MSCs is known as a critical determinant of their fate, the main regulators of stem cell...

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Detalles Bibliográficos
Autores principales: Kwon, Ji Hye, Kim, Miyeon, Um, Soyoun, Lee, Hyang Ju, Bae, Yun Kyung, Choi, Soo Jin, Hwang, Hyun Ho, Oh, Wonil, Jin, Hye Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824096/
https://www.ncbi.nlm.nih.gov/pubmed/33401590
http://dx.doi.org/10.3390/cells10010063