Cargando…
Senescence-Associated Secretory Phenotype Suppression Mediated by Small-Sized Mesenchymal Stem Cells Delays Cellular Senescence through TLR2 and TLR5 Signaling
In order to provide a sufficient number of cells for clinical use, mesenchymal stem cells (MSCs) must be cultured for long-term expansion, which inevitably triggers cellular senescence. Although the small size of MSCs is known as a critical determinant of their fate, the main regulators of stem cell...
Autores principales: | Kwon, Ji Hye, Kim, Miyeon, Um, Soyoun, Lee, Hyang Ju, Bae, Yun Kyung, Choi, Soo Jin, Hwang, Hyun Ho, Oh, Wonil, Jin, Hye Jin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824096/ https://www.ncbi.nlm.nih.gov/pubmed/33401590 http://dx.doi.org/10.3390/cells10010063 |
Ejemplares similares
-
Positively Correlated CD47 Activation and Autophagy in Umbilical Cord Blood-Derived Mesenchymal Stem Cells during Senescence
por: Kim, Gee-Hye, et al.
Publicado: (2021) -
A Small-Sized Population of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Shows High Stemness Properties and Therapeutic Benefit
por: Kim, Miyeon, et al.
Publicado: (2020) -
Decorin Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Induces Macrophage Polarization via CD44 to Repair Hyperoxic Lung Injury
por: Kwon, Ji Hye, et al.
Publicado: (2019) -
CD26 Inhibition Potentiates the Therapeutic Effects of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells by Delaying Cellular Senescence
por: Kim, Miyeon, et al.
Publicado: (2022) -
Soluble PTX3 of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Attenuates Hyperoxic Lung Injury by Activating Macrophage Polarization in Neonatal Rat Model
por: Kim, Miyeon, et al.
Publicado: (2020)