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Manipulating the Metabolism to Improve the Efficacy of CAR T-Cell Immunotherapy
The adoptive transfer of the chimeric antigen receptor (CAR) expressing T-cells has produced unprecedented successful results in the treatment of B-cell malignancies. However, the use of this technology in other malignancies remains less effective. In the setting of solid neoplasms, CAR T-cell metab...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824126/ https://www.ncbi.nlm.nih.gov/pubmed/33374128 http://dx.doi.org/10.3390/cells10010014 |