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Manipulating the Metabolism to Improve the Efficacy of CAR T-Cell Immunotherapy

The adoptive transfer of the chimeric antigen receptor (CAR) expressing T-cells has produced unprecedented successful results in the treatment of B-cell malignancies. However, the use of this technology in other malignancies remains less effective. In the setting of solid neoplasms, CAR T-cell metab...

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Detalles Bibliográficos
Autores principales:	Pellegrino, Marsha, Del Bufalo, Francesca, De Angelis, Biagio, Quintarelli, Concetta, Caruana, Ignazio, de Billy, Emmanuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824126/ https://www.ncbi.nlm.nih.gov/pubmed/33374128 http://dx.doi.org/10.3390/cells10010014

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