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Chitosan-Stabilized Selenium Nanoparticles and Metformin Synergistically Rescue Testicular Oxidative Damage and Steroidogenesis-Related Genes Dysregulation in High-Fat Diet/Streptozotocin-Induced Diabetic Rats

Background: this study examined the metformin (MF) and/or chitosan stabilized selenium nanoparticles (CH-SeNPs) efficacy to alleviate the male reproductive function impairment in a high-fat diet feed with low-dose streptozotocin (HFD/STZ) induced type 2 diabetes mellitus (T2DM) diabetic rat model. M...

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Detalles Bibliográficos
Autores principales: Abd El-Hakim, Yasmina M., Abdel-Rahman Mohamed, Amany, Khater, Safaa I., Hamed Arisha, Ahmed, Metwally, Mohamed M. M., Nassan, Mohamed A., Hassan, Manal Ewaiss
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824144/
https://www.ncbi.nlm.nih.gov/pubmed/33375437
http://dx.doi.org/10.3390/antiox10010017