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Impact of Genetic Variability in ACE2 Expression on the Evolutionary Dynamics of SARS-CoV-2 Spike D614G Mutation

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein D614G mutation became the predominant globally circulating variant after its emergence in the early coronavirus disease 2019 (COVID-19) pandemic. Studies showed that this mutation results in an open conformation...

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Detalles Bibliográficos
Autores principales: Huang, Szu-Wei, Miller, Sorin O., Yen, Chia-Hung, Wang, Sheng-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824201/
https://www.ncbi.nlm.nih.gov/pubmed/33374416
http://dx.doi.org/10.3390/genes12010016