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Development of Anti-Virulence Therapeutics against Mono-ADP-Ribosyltransferase Toxins

Mono-ADP-ribosyltransferase toxins are often key virulence factors produced by pathogenic bacteria as tools to compromise the target host cell. These toxins are enzymes that use host cellular NAD(+) as the substrate to modify a critical macromolecule target in the host cell machinery. This post-tran...

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Detalles Bibliográficos
Autores principales: Lugo, Miguel R., Merrill, Allan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824265/
https://www.ncbi.nlm.nih.gov/pubmed/33375750
http://dx.doi.org/10.3390/toxins13010016