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Development of Anti-Virulence Therapeutics against Mono-ADP-Ribosyltransferase Toxins
Mono-ADP-ribosyltransferase toxins are often key virulence factors produced by pathogenic bacteria as tools to compromise the target host cell. These toxins are enzymes that use host cellular NAD(+) as the substrate to modify a critical macromolecule target in the host cell machinery. This post-tran...
Autores principales: | Lugo, Miguel R., Merrill, Allan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824265/ https://www.ncbi.nlm.nih.gov/pubmed/33375750 http://dx.doi.org/10.3390/toxins13010016 |
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