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Separation of Coiled-Coil Structures in Lamin A/C Is Required for the Elongation of the Filament

Intermediate filaments (IFs) commonly have structural elements of a central α-helical coiled-coil domain consisting of coil 1a, coil 1b, coil 2, and their flanking linkers. Recently, the crystal structure of a long lamin A/C fragment was determined and showed detailed features of a tetrameric unit....

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Detalles Bibliográficos
Autores principales: Ahn, Jinsook, Jeong, Soyeon, Kang, So-Mi, Jo, Inseong, Park, Bum-Joon, Ha, Nam-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824274/
https://www.ncbi.nlm.nih.gov/pubmed/33396475
http://dx.doi.org/10.3390/cells10010055