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Separation of Coiled-Coil Structures in Lamin A/C Is Required for the Elongation of the Filament
Intermediate filaments (IFs) commonly have structural elements of a central α-helical coiled-coil domain consisting of coil 1a, coil 1b, coil 2, and their flanking linkers. Recently, the crystal structure of a long lamin A/C fragment was determined and showed detailed features of a tetrameric unit....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824274/ https://www.ncbi.nlm.nih.gov/pubmed/33396475 http://dx.doi.org/10.3390/cells10010055 |