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ApoE-Targeting Increases the Transfer of Solid Lipid Nanoparticles with Donepezil Cargo across a Culture Model of the Blood–Brain Barrier

Pharmacological treatment of central nervous system (CNS) disorders is difficult, because the blood–brain barrier (BBB) restricts the penetration of many drugs into the brain. To solve this unmet therapeutic need, nanosized drug carriers are the focus of research efforts to develop drug delivery sys...

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Detalles Bibliográficos
Autores principales: Topal, Gizem Rüya, Mészáros, Mária, Porkoláb, Gergő, Szecskó, Anikó, Polgár, Tamás Ferenc, Siklós, László, Deli, Mária A., Veszelka, Szilvia, Bozkir, Asuman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824445/
https://www.ncbi.nlm.nih.gov/pubmed/33383743
http://dx.doi.org/10.3390/pharmaceutics13010038