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Distinct p63 and p73 Protein Interactions Predict Specific Functions in mRNA Splicing and Polyploidy Control in Epithelia

Epithelial organs are the first barrier against microorganisms and genotoxic stress, in which the p53 family members p63 and p73 have both overlapping and distinct functions. Intriguingly, p73 displays a very specific localization to basal epithelial cells in human tissues, while p63 is expressed in...

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Detalles Bibliográficos
Autores principales: Rozenberg, Julian M., Rogovaya, Olga S., Melino, Gerry, Barlev, Nickolai A., Kagansky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824480/
https://www.ncbi.nlm.nih.gov/pubmed/33375680
http://dx.doi.org/10.3390/cells10010025