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Microbial Antigen-Presenting Extracellular Vesicles Derived from Genetically Modified Tumor Cells Promote Antitumor Activity of Dendritic Cells

Tumor-derived extracellular vesicles (EVs), as tumor vaccines, carry tumor-associated antigens (TAAs), and were expected to transfer TAAs to antigen-presenting cells. However, treatment with tumor-derived EVs exhibited no obvious antitumor effect on the established tumors, likely due to their immuno...

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Detalles Bibliográficos
Autores principales: Ito, Tomoko, Sugiura, Kikuya, Hasegawa, Aya, Ouchi, Wakana, Yoshimoto, Takayuki, Mizoguchi, Izuru, Inaba, Toshio, Hamada, Katsuyuki, Eriguchi, Masazumi, Koyama, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824503/
https://www.ncbi.nlm.nih.gov/pubmed/33406722
http://dx.doi.org/10.3390/pharmaceutics13010057