Gabapentin and Duloxetine Prevent Oxaliplatin- and Paclitaxel-Induced Peripheral Neuropathy by Inhibiting Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Phosphorylation in Spinal Cords of Mice

Chemotherapy-induced peripheral neuropathy is a common factor in limiting therapy which can result in therapy cessation or dose reduction. Gabapentin, a calcium channel inhibitor, and duloxetine, a serotonin noradrenaline reuptake inhibitor, are used to treat a variety of pain conditions such as chr...

Descripción completa

Detalles Bibliográficos
Autores principales: Kato, Natsuki, Tateishi, Keisuke, Tsubaki, Masanobu, Takeda, Tomoya, Matsumoto, Mikihiro, Tsurushima, Katsumasa, Ishizaka, Toshihiko, Nishida, Shozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824557/
https://www.ncbi.nlm.nih.gov/pubmed/33396362
http://dx.doi.org/10.3390/ph14010030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824557/
https://www.ncbi.nlm.nih.gov/pubmed/33396362
http://dx.doi.org/10.3390/ph14010030

Ejemplares similares