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Gabapentin and Duloxetine Prevent Oxaliplatin- and Paclitaxel-Induced Peripheral Neuropathy by Inhibiting Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Phosphorylation in Spinal Cords of Mice

Chemotherapy-induced peripheral neuropathy is a common factor in limiting therapy which can result in therapy cessation or dose reduction. Gabapentin, a calcium channel inhibitor, and duloxetine, a serotonin noradrenaline reuptake inhibitor, are used to treat a variety of pain conditions such as chr...

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Detalles Bibliográficos
Autores principales:	Kato, Natsuki, Tateishi, Keisuke, Tsubaki, Masanobu, Takeda, Tomoya, Matsumoto, Mikihiro, Tsurushima, Katsumasa, Ishizaka, Toshihiko, Nishida, Shozo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824557/ https://www.ncbi.nlm.nih.gov/pubmed/33396362 http://dx.doi.org/10.3390/ph14010030

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