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Combined Effect of Caspase-Dependent and Caspase-Independent Apoptosis in the Anticancer Activity of Gold Complexes with Phosphine and Benzimidazole Derivatives

Since the potential anticancer activity of auranofin was discovered, gold compounds have attracted interest with a view to developing anticancer agents that follow cytotoxic mechanisms other than cisplatin. Two benzimidazole gold(I) derivatives containing triphenylphosphine (Au(pben)(PPh(3))) (1) or...

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Detalles Bibliográficos
Autores principales: Rouco, Lara, Sánchez-González, Ángeles, Alvariño, Rebeca, Alfonso, Amparo, Vázquez-López, Ezequiel M., García-Martínez, Emilia, Maneiro, Marcelino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824672/
https://www.ncbi.nlm.nih.gov/pubmed/33374177
http://dx.doi.org/10.3390/ph14010010