Molecular and Biochemical Techniques for Deciphering p53-MDM2 Regulatory Mechanisms

The p53 and Mouse double minute 2 (MDM2) proteins are hubs in extensive networks of interactions with multiple partners and functions. Intrinsically disordered regions help to adopt function-specific structural conformations in response to ligand binding and post-translational modifications. Differe...

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Detalles Bibliográficos
Autores principales: Karakostis, Konstantinos, López, Ignacio, Peña-Balderas, Ana M., Fåhareus, Robin, Olivares-Illana, Vanesa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824699/
https://www.ncbi.nlm.nih.gov/pubmed/33396576
http://dx.doi.org/10.3390/biom11010036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824699/
https://www.ncbi.nlm.nih.gov/pubmed/33396576
http://dx.doi.org/10.3390/biom11010036

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