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Molecular and Biochemical Techniques for Deciphering p53-MDM2 Regulatory Mechanisms
The p53 and Mouse double minute 2 (MDM2) proteins are hubs in extensive networks of interactions with multiple partners and functions. Intrinsically disordered regions help to adopt function-specific structural conformations in response to ligand binding and post-translational modifications. Differe...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824699/ https://www.ncbi.nlm.nih.gov/pubmed/33396576 http://dx.doi.org/10.3390/biom11010036 |