Shiga Toxin 2a Binds to Complement Components C3b and C5 and Upregulates Their Gene Expression in Human Cell Lines

Enterohemorrhagic Escherichia coli (EHEC) infections can cause EHEC-associated hemolytic uremic syndrome (eHUS) via its main virulent factor, Shiga toxins (Stxs). Complement has been reported to be involved in the progression of eHUS. The aim of this study was to investigate the interactions of the...

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Detalles Bibliográficos
Autores principales: Kellnerová, Sára, Chatterjee, Sneha, Bayarri-Olmos, Rafael, Justesen, Louise, Talasz, Heribert, Posch, Wilfried, Kenno, Samyr, Garred, Peter, Orth-Höller, Dorothea, Grasse, Marco, Würzner, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824702/
https://www.ncbi.nlm.nih.gov/pubmed/33374102
http://dx.doi.org/10.3390/toxins13010008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824702/
https://www.ncbi.nlm.nih.gov/pubmed/33374102
http://dx.doi.org/10.3390/toxins13010008

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