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Shiga Toxin 2a Binds to Complement Components C3b and C5 and Upregulates Their Gene Expression in Human Cell Lines
Enterohemorrhagic Escherichia coli (EHEC) infections can cause EHEC-associated hemolytic uremic syndrome (eHUS) via its main virulent factor, Shiga toxins (Stxs). Complement has been reported to be involved in the progression of eHUS. The aim of this study was to investigate the interactions of the...
Autores principales: | Kellnerová, Sára, Chatterjee, Sneha, Bayarri-Olmos, Rafael, Justesen, Louise, Talasz, Heribert, Posch, Wilfried, Kenno, Samyr, Garred, Peter, Orth-Höller, Dorothea, Grasse, Marco, Würzner, Reinhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824702/ https://www.ncbi.nlm.nih.gov/pubmed/33374102 http://dx.doi.org/10.3390/toxins13010008 |
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