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Insights into the Interaction Mechanism of DTP3 with MKK7 by Using STD-NMR and Computational Approaches
GADD45 [Formula: see text] /MKK7 complex is a non-redundant, cancer cell-restricted survival module downstream of the NF-kB survival pathway, and it has a pathogenically critical role in multiple myeloma, an incurable malignancy of plasma cells. The first-in-class GADD45 [Formula: see text] /MKK7 in...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824710/ https://www.ncbi.nlm.nih.gov/pubmed/33396582 http://dx.doi.org/10.3390/biomedicines9010020 |