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Rhosin Suppressed Tumor Cell Metastasis through Inhibition of Rho/YAP Pathway and Expression of RHAMM and CXCR4 in Melanoma and Breast Cancer Cells

The high mortality rate of cancer is strongly correlated with the development of distant metastases at secondary sites. Although Rho GTPases, such as RhoA, RhoB, RhoC, and RhoE, promote tumor metastasis, the main roles of Rho GTPases remain unidentified. It is also unclear whether rhosin, a Rho inhi...

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Detalles Bibliográficos
Autores principales: Tsubaki, Masanobu, Genno, Shuuji, Takeda, Tomoya, Matsuda, Takuya, Kimura, Naoto, Yamashita, Yuuma, Morii, Yuusuke, Shimomura, Kazunori, Nishida, Shozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824767/
https://www.ncbi.nlm.nih.gov/pubmed/33406809
http://dx.doi.org/10.3390/biomedicines9010035