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Identification of Small Molecules Blocking the Pseudomonas aeruginosa Type III Secretion System Protein PcrV

Pseudomonas aeruginosa is an opportunistic bacterial pathogen that employs its type III secretion system (T3SS) during the acute phase of infection to translocate cytotoxins into the host cell cytoplasm to evade the immune system. The PcrV protein is located at the tip of the T3SS, facilitates the i...

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Detalles Bibliográficos
Autores principales: Sundin, Charlotta, Saleeb, Michael, Spjut, Sara, Qin, Liena, Elofsson, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824769/
https://www.ncbi.nlm.nih.gov/pubmed/33406810
http://dx.doi.org/10.3390/biom11010055