Alcohol-and-HIV-Induced Lysosomal Dysfunction Regulates Extracellular Vesicles Secretion in Vitro and in Liver-Humanized Mice

SIMPLE SUMMARY: Consumption of alcohol increases liver damage in HIV people; however, the mechanisms remain elusive. By utilizing alcohol (ethanol) exposed HIV-infected human hepatocytes liver cells and ethanol-fed liver humanized mouse model (immunodeficient mice livers harbor human hepatocytes), w...

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Detalles Bibliográficos
Autores principales: Dagur, Raghubendra Singh, New-Aaron, Moses, Ganesan, Murali, Wang, Weimin, Romanova, Svetlana, Kidambi, Srivatsan, Kharbanda, Kusum K., Poluektova, Larisa Y., Osna, Natalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824801/
https://www.ncbi.nlm.nih.gov/pubmed/33466299
http://dx.doi.org/10.3390/biology10010029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824801/
https://www.ncbi.nlm.nih.gov/pubmed/33466299
http://dx.doi.org/10.3390/biology10010029

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