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SZR-104, a Novel Kynurenic Acid Analogue with High Permeability through the Blood–Brain Barrier

By being an antagonist of glutamate and other receptors, kynurenic acid serves as an endogenous neuroprotectant in several pathologies of the brain. Unfortunately, systemic administration of kynurenic acid is hindered by its low permeability through the blood–brain barrier. One possibility to overco...

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Detalles Bibliográficos
Autores principales: Molnár, Kinga, Lőrinczi, Bálint, Fazakas, Csilla, Szatmári, István, Fülöp, Ferenc, Kmetykó, Noémi, Berkecz, Róbert, Ilisz, István, Krizbai, István A., Wilhelm, Imola, Vécsei, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824826/
https://www.ncbi.nlm.nih.gov/pubmed/33466551
http://dx.doi.org/10.3390/pharmaceutics13010061