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SZR-104, a Novel Kynurenic Acid Analogue with High Permeability through the Blood–Brain Barrier
By being an antagonist of glutamate and other receptors, kynurenic acid serves as an endogenous neuroprotectant in several pathologies of the brain. Unfortunately, systemic administration of kynurenic acid is hindered by its low permeability through the blood–brain barrier. One possibility to overco...
Autores principales: | Molnár, Kinga, Lőrinczi, Bálint, Fazakas, Csilla, Szatmári, István, Fülöp, Ferenc, Kmetykó, Noémi, Berkecz, Róbert, Ilisz, István, Krizbai, István A., Wilhelm, Imola, Vécsei, László |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824826/ https://www.ncbi.nlm.nih.gov/pubmed/33466551 http://dx.doi.org/10.3390/pharmaceutics13010061 |
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