A Monoclonal Antibody Combination against both Serotypes A and B Botulinum Toxin Prevents Inhalational Botulism in a Guinea Pig Model

Botulinum neurotoxins (BoNT) are extremely potent and can induce respiratory failure, requiring long-term intensive care to prevent death. Recombinant monoclonal antibodies (mAbs) hold considerable promise as BoNT therapeutics and prophylactics. In contrast, equine antitoxin cannot be used prophylac...

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Detalles Bibliográficos
Autores principales: Snow, Doris M., Cobb, Ronald R., Martinez, Juan, Finger-Baker, Isaac, Collins, Laura, Terpening, Sara, Syar, Emily S., Niemuth, Nancy, Kobs, Dean, Barnewall, Roy, Farr-Jones, Shauna, Marks, James D., Tomic, Milan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824882/
https://www.ncbi.nlm.nih.gov/pubmed/33466411
http://dx.doi.org/10.3390/toxins13010031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824882/
https://www.ncbi.nlm.nih.gov/pubmed/33466411
http://dx.doi.org/10.3390/toxins13010031

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