A Monoclonal Antibody Combination against both Serotypes A and B Botulinum Toxin Prevents Inhalational Botulism in a Guinea Pig Model

Botulinum neurotoxins (BoNT) are extremely potent and can induce respiratory failure, requiring long-term intensive care to prevent death. Recombinant monoclonal antibodies (mAbs) hold considerable promise as BoNT therapeutics and prophylactics. In contrast, equine antitoxin cannot be used prophylac...

Descripción completa

Detalles Bibliográficos
Autores principales: Snow, Doris M., Cobb, Ronald R., Martinez, Juan, Finger-Baker, Isaac, Collins, Laura, Terpening, Sara, Syar, Emily S., Niemuth, Nancy, Kobs, Dean, Barnewall, Roy, Farr-Jones, Shauna, Marks, James D., Tomic, Milan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824882/
https://www.ncbi.nlm.nih.gov/pubmed/33466411
http://dx.doi.org/10.3390/toxins13010031

Ejemplares similares

Ejemplares similares