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The Insulin Receptor Mediates Insulin’s Early Plasma Clearance by Liver, Muscle, and Kidney
The role of the insulin receptor in mediating tissue-specific insulin clearance in vivo has not been reported. Using physiologic insulin doses, we measured the initial clearance rate (first 5 min) of intravenously injected ([(125)I]Tyr(A14))-insulin by muscle, liver, and kidney in healthy rats in th...
Autores principales: | Meijer, Rick I., Barrett, Eugene J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824884/ https://www.ncbi.nlm.nih.gov/pubmed/33466380 http://dx.doi.org/10.3390/biomedicines9010037 |
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