Alternative Splicing Increases Sirtuin Gene Family Diversity and Modulates Their Subcellular Localization and Function

Alternative splicing generates multiple distinct isoforms that increase transcriptome and proteome diversity. There are seven sirtuin genes in humans, each consists of multiple exons that are likely to undergo alternative splicing. Our aim was to characterize the effect of alternative splicing on th...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaomin, Ameer, Fathima S., Azhar, Gohar, Wei, Jeanne Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824890/
https://www.ncbi.nlm.nih.gov/pubmed/33418837
http://dx.doi.org/10.3390/ijms22020473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824890/
https://www.ncbi.nlm.nih.gov/pubmed/33418837
http://dx.doi.org/10.3390/ijms22020473

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