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Time-course single-cell RNA sequencing reveals transcriptional dynamics and heterogeneity of limbal stem cells derived from human pluripotent stem cells

BACKGROUND: Human pluripotent stem cell-derived limbal stem cells (hPSC-derived LSCs) provide a promising cell source for corneal transplants and ocular surface reconstruction. Although recent efforts in the identification of LSC markers have increased our understanding of the biology of LSCs, much...

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Detalles Bibliográficos
Autores principales: Sun, Changbin, Wang, Hailun, Ma, Qiwang, Chen, Chao, Yue, Jianhui, Li, Bo, Zhang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824938/
https://www.ncbi.nlm.nih.gov/pubmed/33485387
http://dx.doi.org/10.1186/s13578-021-00541-4