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Methods to investigate intrathecal adaptive immunity in neurodegeneration

BACKGROUND: Cerebrospinal fluid (CSF) provides basic mechanical and immunological protection to the brain. Historically, analysis of CSF has focused on protein changes, yet recent studies have shed light on cellular alterations. Evidence now exists for involvement of intrathecal T cells in the patho...

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Detalles Bibliográficos
Autores principales: Oh, Hamilton, Leventhal, Olivia, Channappa, Divya, Henderson, Victor W., Wyss-Coray, Tony, Lehallier, Benoit, Gate, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824942/
https://www.ncbi.nlm.nih.gov/pubmed/33482851
http://dx.doi.org/10.1186/s13024-021-00423-w