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GABA(B)-Receptor Agonist-Based Immunotherapy for Type 1 Diabetes in NOD Mice

Some immune system cells express type A and/or type B γ-aminobutyric acid receptors (GABA(A)-Rs and/or GABA(B)-Rs). Treatment with GABA, which activates both GABA(A)-Rs and GABA(B)-Rs), and/or a GABA(A)-R-specific agonist inhibits disease progression in mouse models of type 1 diabetes (T1D), multipl...

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Detalles Bibliográficos
Autores principales: Tian, Jide, Middleton, Blake, Lee, Victoria Seunghee, Park, Hye Won, Zhang, Zhixuan, Kim, Bokyoung, Lowe, Catherine, Nguyen, Nancy, Liu, Haoyuan, Beyer, Ryan S., Chao, Hannah W., Chen, Ryan, Mai, Davis, O’Laco, Karen Anne, Song, Min, Kaufman, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825043/
https://www.ncbi.nlm.nih.gov/pubmed/33418884
http://dx.doi.org/10.3390/biomedicines9010043