Molecular Targeting of HuR Oncoprotein Suppresses MITF and Induces Apoptosis in Melanoma Cells

SIMPLE SUMMARY: The human antigen R (HuR) protein regulates the expression of hundreds of proteins in a cell that support tumor growth, drug resistance, and metastases. HuR is overexpressed in several human cancers, including melanoma, and is a molecular target for cancer therapy. Our study objectiv...

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Detalles Bibliográficos
Autores principales: Ahmed, Rebaz, Muralidharan, Ranganayaki, Srivastava, Akhil, Johnston, Sarah E., Zhao, Yan D., Ekmekcioglu, Suhendan, Munshi, Anupama, Ramesh, Rajagopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825065/
https://www.ncbi.nlm.nih.gov/pubmed/33418925
http://dx.doi.org/10.3390/cancers13020166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825065/
https://www.ncbi.nlm.nih.gov/pubmed/33418925
http://dx.doi.org/10.3390/cancers13020166

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