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Molecular Targeting of HuR Oncoprotein Suppresses MITF and Induces Apoptosis in Melanoma Cells
SIMPLE SUMMARY: The human antigen R (HuR) protein regulates the expression of hundreds of proteins in a cell that support tumor growth, drug resistance, and metastases. HuR is overexpressed in several human cancers, including melanoma, and is a molecular target for cancer therapy. Our study objectiv...
Autores principales: | Ahmed, Rebaz, Muralidharan, Ranganayaki, Srivastava, Akhil, Johnston, Sarah E., Zhao, Yan D., Ekmekcioglu, Suhendan, Munshi, Anupama, Ramesh, Rajagopal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825065/ https://www.ncbi.nlm.nih.gov/pubmed/33418925 http://dx.doi.org/10.3390/cancers13020166 |
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