Downregulation of miR-17-92 Cluster by PERK Fine-Tunes Unfolded Protein Response Mediated Apoptosis

An important event in the unfolded protein response (UPR) is activation of the endoplasmic reticulum (ER) kinase PERK. The PERK signalling branch initially mediates a prosurvival response, which progresses to a proapoptotic response upon prolonged ER stress. However, the molecular mechanisms of PERK...

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Detalles Bibliográficos
Autores principales: Read, Danielle E., Gupta, Ananya, Cawley, Karen, Fontana, Laura, Agostinis, Patrizia, Samali, Afshin, Gupta, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825066/
https://www.ncbi.nlm.nih.gov/pubmed/33418948
http://dx.doi.org/10.3390/life11010030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825066/
https://www.ncbi.nlm.nih.gov/pubmed/33418948
http://dx.doi.org/10.3390/life11010030

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