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PD-L1/PD-1 Axis in Multiple Myeloma Microenvironment and a Possible Link with CD38-Mediated Immune-Suppression

SIMPLE SUMMARY: Despite the impressive clinical impact of programmed death-ligand 1 (PD-L1)/programmed cell death-1 (PD-1) blockade in solid tumors, the use of these checkpoint inhibitors in multiple myeloma (MM) still remains debated with unsatisfying clinically meaningful results. In this review w...

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Detalles Bibliográficos
Autores principales: Costa, Federica, Marchica, Valentina, Storti, Paola, Malavasi, Fabio, Giuliani, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825118/
https://www.ncbi.nlm.nih.gov/pubmed/33418913
http://dx.doi.org/10.3390/cancers13020164